New Quiz 26 Jan Welcome to your MLT- Professional Name: Email: Phone Number: [Which statement accurately describes the clinical utility of translocation testing in leukemia?] Relapse is predicted by any new translocation occurring after treatment Specific translocations associated with a type of leukemia will occur in all cases Translocation products for each leukemia subtype are always the same Translocation is a sensitive way to identify surviving leukemic cells following treatment None . [Which of the following statements accurately describes hCG levels in pregnancy?] Levels of hCG rise throughout pregnancy In ectopic pregnancy, serum hCG doubling time is below expected levels Molar pregnancies are associated with lower levels than expected for the time of gestation hCG returns to nonpregnant levels within 2 days following delivery, stillbirth, or abortion None . [Which of the following disorders is associated with ineffective erythropoiesis?] G6PD deficiency Liver disease Hgb C disease Megaloblastic anemia None . [Which is the reference method for determining fetal lung maturity?] Human placental lactogen L/S ratio Amniotic fluid bilirubin Urinary estriol None . [Under CLIA ’88, testing personnel with an associate degree and appropriate training in the clinical laboratory are authorized to perform:] Waived tests only Tests that are qualitative or waived and some moderate-complexity tests Waived and moderate-complexity tests Waived, moderate-complexity, and highcomplexity tests None . [FISH can distinguish each of the following chromosomal abnormalities except:] Aneuploidy Translocation Deletion Trinucleotide repeats None . [Which assay result is often approximately 25% below the expected level in pregnancies associated with Down syndrome?] Serum unconjugated estriol L/S ratio Amniotic fluid bilirubin Urinary chorionic gonadotropin None . [A patient is admitted to the hospital. Medical records indicate that the patient has a history of anti-Jka. When you performed the type and screen, the type was O positive and screen was negative. You should:] Crossmatch using units negative for Jka antigen Crossmatch random units, since the antibody is not demonstrating Request a new sample Repeat the screen with enzyme-treated screening cells None . [A 12-year old girl has symptoms of fatigue and a localized lymphadenopathy. Laboratory tests reveal a peripheral blood lymphocytosis, a positive RPR, and a positive spot test for IM. What test should be performed next?] HIV test by ELISA VDRL Epstein–Barr virus (EBV) specific antigen test Treponema pallidum particle agglutination (TP-PA) test None . [The material safety data sheets (MSDSs) for hazardous chemicals address which of the following conditions?] Physical characteristics of the chemical Safe handling and storage of the chemical Specific health hazards associated with the chemical All of these options None . [A brown or black pigment in urine can be caused by:] Gantrisin (Pyridium) Phenolsulfonphthalein Rifampin Melanin None . [Which of the following fluids is associated with the lungs?] Gastric Peritoneal Pleural Synovial None . [Streptococcus species exhibit which of the following properties?] Aerobic, oxidase positive, and catalase positive Facultative anaerobe, oxidase negative, catalase negative Facultative anaerobe, β-hemolytic, catalase positive May be α-, β-, or γ-hemolytic, catalase positive None . [Plate 26 is a urinary sediment viewed under 400× magnification using a brightfield microscope. Which type of cast is present?] Hyaline cast Broad cast Waxy cast Coarse granular cast None Comment . [What techniques are necessary for weak D testing?] Saline + 22°C incubation Albumin or LISS + 37°C incubation Saline + 37°C incubation 37°C incubation + IAT None . Hodgkin’s lymphoma Myeloproliferative disorder Leukemoid reaction Acute lymphocytic leukemia None Comment . [Cystitis means:] blueness of the skin. cellular infection. infl ammation of the bladder. pertaining to a cell. None . [Plate 56 is a Papanicolaou-stained seminal fluid, 1,000× magnification. What is the round cell near the center of the field?] WBC Primary spermatocyte Histiocyte Spermatid None Comment . [Which of the following conditions is classified as normochloremic acidosis?] Diabetic ketoacidosis Chronic pulmonary obstruction Uremic acidosis Diarrhea None . [This type of antibody response is analogous to an anamnestic antibody reaction.] Primary Secondary Tertiary Anaphylactic None . [How can cell proliferation be explained by the BCR/ABL gene rearrangement that occurs in the 9:22 translocation that causes the Ph1 chromosome of CML?] It causes underexpression of p53 A hybrid protein is made that up-regulates the cell cycle Translocation induces a point mutation in the ABL oncogene ABL activates p23 None . [Review the following CBC results on a 2-day-old infant: WBCs = 15.2 × 10^9/L MCV = 105 fLRBCs = 5.30 × 10^12/L MCH = 34.0 pgHgb = 18.5 g/dL MCHC = 33.5%Hct = 57.9% PLT = 213 × 10^9/LThese results indicate:] Macrocytic anemia Microcytic anemia Liver disease Normal values for a 2-day-old infant None Comment . [The principles of right and wrong conduct as they apply to professional problems are called:] certification. esteem. ethics. torts. None . [The breakpoint of an antimicrobial drug refers to:] The amount needed to cause bacteriostasis A minimum inhibitory concentration (MIC) of 16 μg/mL or greater A MIC of 64 μg/mL or greater The level of drug that is achievable in serum None . [Orders for uric acid are legitimate stat requests because:] Levels above 10 mg/dL cause urinary tract calculi Uric acid is hepatotoxic High levels induce aplastic anemia High levels cause joint pain None . [Six units are crossmatched. Five units are compatible, one unit is incompatible, and the recipient’s antibody screen is negative. Identify the problem:] Patient may have an alloantibody to a high-frequency antigen Patient may have an abnormal protein Donor unit may have a positive DAT Donor may have a high-frequency antigen None . [Which of the following statements regarding ALP is true?] In normal adults, the primary tissue source is fast-twitch skeletal muscle Geriatric patients have a lower serum ALP than other adults Serum ALP levels are lower in children than in adults Pregnant women have a higher level of serum ALP than other adults None . [In double immunodiffusion reactions, the precipitin band is:] Invisible before the equivalence point is reached Concave to the protein of greatest molecular weight Closest to the well containing the highest level of antigen Located in an area of antibody excess None . [Most cases of Down syndrome are the result of:] Nondisjunction of an E chromosome (E trisomy) Nondisjunction of chromosome 21 (G trisomy) A 14–21 chromosome translocation Deletion of the long arm of chromosome 21 None . [Which group of tests best identifies the Morganella and Proteus genera?] Motility, urease, and phenylalanine deaminase Malonate, glucose fermentation, and deoxyribonuclease (DNase) Indole, oxidase, MR, and VP Indole, citrate, and urease None . Time's up